Study links phthalates to asthma

Mike Verespej

Published: September 7, 2012 6:00 am ET

Related to this story

Topics Sustainability, Public Policy, Materials, Suppliers

NEW YORK (Sept. 7, 2:20 p.m. ET) — A new research study says that children between the ages of 5 and 9 who are exposed to two types of phthalates found in personal-care products have an elevated risk of asthma-related airway inflammation.

The study — conducted by the Columbia Center for Children’s Environmental Health in New York — found that all of the 244 children had detectable levels of phthalates in their urine, as well as higher levels of diethyl phthalate and butylbenzyl phthalate in their urine samples.

The researchers said the higher level of phthalates in those urine samples were associated with higher levels of nitric oxide in their exhaled breath, a biological marker of airway inflammation.

The association between BBzP exposure and airway inflammation was especially strong among children who had recently reported wheeze, a common symptom of asthma, said the researchers.

“While many factors contribute to childhood asthma, our study shows that exposure to phthalates may play a significant role,” said Allan Just, a postdoctoral researcher at the Harvard School of Public Health and lead author of the report.

The study did not specify what type of products with phthalates the children in the study might have been exposed to. All the children live in northern Manhattan and the south Bronx, where asthma prevalence is high.

It is the first study to use exhaled nitric oxide in a study of phthalate exposure in children.

“Many asthma patients only have asthma exacerbations a few times a year, making it difficult to discern short-term associations between environmental exposures and the disease,” said Matthew Perzanowski, senior author of the report and associate professor of environmental health sciences at the Mailman School of Public Health at Columbia University. “To solve this problem, we used nitric oxide, which has been shown to be a reliable marker of airway inflammation in response to known asthma triggers like vehicle emissions.”

“The study by the Columbia Center should be interpreted with great caution,” said Steve Risotto, senior director of the phthalates ester panel at the American Chemistry Council in Washington.

“The report is based on a single measurement of phthalate meta­bolite concentrations and fails to recognize that phthalates are broken down within hours and quickly eliminated from the body,” while the airway inflammation measured might take days or even weeks to manifest itself.

“Importantly the authors note that they found ‘no direct association’ between any of the phthalate metabolites and more traditional measures of asthma and allergy among the children tested,” Risotto said.


Comments

Study links phthalates to asthma

Mike Verespej

Published: September 7, 2012 6:00 am ET

Post Your Comments


Back to story


More stories

Some medical devices could get faster approval with new FDA rules

April 22, 2014 7:41 pm ET

The U.S. Food and Drug Administration is proposing an expedited approval for medical devices for devices aimed at the diagnosis or treatment of...    More

Image

Two Ohio groups team up to accelerate development of future medical devices

April 22, 2014 9:55 am ET

The Austen BioInnovation Institute in Akron and Cleveland-based design specialists Nottingham Spirk announced a strategic partnership that the two...    More

Image

Coffee roaster looks to improve footprint of single cup systems

April 22, 2014 1:30 pm ET

One of the largest coffee and tea manufacturers in North America has introduced a single-serve beverage capsule intended to curb the waste created by ...    More

Image

HRS adding more North American production for hot runners

April 22, 2014 12:57 pm ET

An Italian tooling component supplier is set to open a new production plant in Grand Rapids, Mich. The HRS Flow Division of San Polo di Piace-...    More

Two Eastman buildings among 10 biggest energy savers in national contest

April 22, 2014 11:35 am ET

Two offices at the headquarters of Eastman Chemical Co. in Kingsport, Tenn., ranked in the Top 10 for energy efficiency in the latest Energy Star Nati...    More

Market Reports

Thermoformed Packaging 2014 Market Review & Outlook North America

This in-depth report provides analysis and discussions of economic and political conditions, market trends, legislative/regulatory activity impacting supply and demand, business opportunities and threats, materials pricing, manufacturing technology, as well as strategies being implemented by thermoformed packaging companies. In addition, there are reviews of 25 leading thermoformers in the packaging segment, assessing their growth initiatives and performance metrics over 10 years.

Learn more

Automotive Market Review and Outlook 2014 The Americas

This 75-page report features in-depth analysis of the automotive industry for the Americas. It includes discussions of market trends, legislative/regulatory activity impacting production and threats as well as design strategies being implemented by the major automakers. Detailed charts and data tables outline North American automotive production over the last five years.

Learn more

Plastics Building & Construction Market Review and Outlook 2014 with MS Excel chart data

This report provides in-depth analysis of the plastic building and construction market for North America, including discussions of trends, opportunities, threats and the latest developments in construction trends that impact plastics processors.

Learn more

Upcoming Plastics News Events

May 6, 2014 - May 8, 2014Plastics in Medical Devices 2014

May 12, 2014 - May 12, 2014Plastics News Brazil Pharma Summit

September 10, 2014 - September 12, 2014Plastics Caps & Closures 2014

February 3, 2015 - February 7, 2015Plastics News Executive Forum 2015

More Events