Study says medical urethanes may suffer hydrolysis

Published: December 10, 2012 6:00 am ET

Related to this story

Topics Medical, Materials, Suppliers

WASHINGTON (Dec. 10, 11:15 a.m. ET) — Researchers have discovered what they call a “previously unrecognized” way that degradation can occur in silicone-urethane plastics, often used in medical devices.

The study, published in the American Chemistry Society’s journal Macromolecules, could have implications for device manufacturers considering use of these plastics in the design of some implantable devices, including cardiac defibrillation leads, ACS said in a Dec. 5 statement.

The researchers said that some implanted biomedical devices, such as pacemakers and defibrillators, have parts made of a plastic consisting of polyurethane and silicone. While these materials have been extensively studied for failure due to interaction with oxygen, no published study has looked at interaction with water as a potential failure mechanism in this class of materials, ACS reported.

In a cardiac lead application, these materials may be used as a coating on the electrical wires that carry electric current from the battery in the device to the heart. Surgeons implant pacemakers in 600,000 people worldwide and defibrillators in 100,000 people in the United States each year, ACS said. Since these implants must function reliably for years, the scientists wanted to determine whether the plastic material was suitable for long-term implants.

ACS reported that laboratory tests, including accelerated ageing of the materials under conditions that simulated the inside of the human body, found indications that the material begins to break down within 3-6 years.

“By making the conclusions of this novel, scientific research public in a respected peer-reviewed journal, device manufacturers may now consider these important findings in their device designs,” commented Kimberley Chaffin, lead author of the report.


Comments

Study says medical urethanes may suffer hydrolysis

Published: December 10, 2012 6:00 am ET

Post Your Comments


Back to story


More stories

Sumitomo Bakelite buying injection molder Vaupell Holdings

April 24, 2014 7:37 pm ET

Private equity firm H.I.G. Capital LLC of Miami has entered into a definitive agreement to sell plastics processor Vaupell Holdings Inc. to Sumitomo...    More

Image

Plastics News Now: Simpsons go Lego, Pharrell Williams gets into recycled plastic

April 24, 2014 8:45 am ET

Lego has teamed up with "The Simpsons" for a special episode, we see the trends at the International Home + Housewares Show and musician Pharrell...    More

Zimmer buying Biomet in $13 billion deal

April 24, 2014 4:25 pm ET

Orthopedic device giant Zimmer Holdings Inc. is buying rival Biomet Inc. in a $13.35 billion cash and stock deal, the companies announced April 24.    More

Image

PolyOne says new Shanghai center will ease collaboration across segments

April 24, 2014 2:34 pm ET

PolyOne Specialty Engineered Materials is opening an innovation Center in Shanghai's Jinqiao development zone that will serve as its new Asia Pacific ...    More

Injection molder Precision Plastics adding space, presses in Indiana

April 24, 2014 2:54 pm ET

Custom injection molder Precision Plastics Inc. is expanding its Columbia City, Ind., operation.    More

Market Reports

Market Data Book - Rankings & Lists

A one-stop download of Plastic News' exclusive annual lists and processor rankings containing essential data including sales, employees, end markets, materials and more.
EXCLUSIVE EXCEL FEATURE: full mailing address details for available plant locations.

Learn more

Thermoformed Packaging 2014 Market Review & Outlook North America

This in-depth report provides analysis and discussions of economic and political conditions, market trends, legislative/regulatory activity impacting supply and demand, business opportunities and threats, materials pricing, manufacturing technology, as well as strategies being implemented by thermoformed packaging companies. In addition, there are reviews of 25 leading thermoformers in the packaging segment, assessing their growth initiatives and performance metrics over 10 years.

Learn more

Mold Making and Tooling Review and Outlook 2014 North America

This report provides in-depth analysis of the mold and toolmaking market for North America, including discussions of trends, opportunities, threats, the latest developments in production and labor and equipment trends impacting moldmakers.

Learn more

Upcoming Plastics News Events

May 6, 2014 - May 8, 2014Plastics in Medical Devices 2014

May 12, 2014 - May 12, 2014Plastics News Brazil Pharma Summit

September 10, 2014 - September 12, 2014Plastics Caps & Closures 2014

February 3, 2015 - February 7, 2015Plastics News Executive Forum 2015

More Events