Lubrizol says new materials will bring more TPU to medical devices

By Gayle S. Putrich
Staff Reporter

Published: June 13, 2014 12:06 pm ET
Updated: June 13, 2014 12:14 pm ET

Image By: Lubrizol Corp. Lubrizol Corp. says its new Pathway pharmaceutical-grade excipient will increase the use of thermoplastic polyurethane in implantable drug release devices.

Related to this story

Topics Medical, Materials, Materials Suppliers

NEW YORK — Lubrizol Corp. introduced a medical-grade thermoplastic polyurethane with flame-retardant properties and a new pharmaceutical excipient for implantable controlled-release drug delivery June 10 at the Medical Design & Manufacturing East conference and trade show in New York.

The flame retardant TPU will be part of the Wickliffe, Ohio-based company’s Tecothane line and offered in five different grades, all designed to meet the exacting requirements of health care applications — including ISO 10993-5 test cytotoxicity requirements and sterilization needs — while still enhancing patient comfort, said Robert Miller business development director for Lubrizol LifeScience Polymers.

The new TPU, available in matte, can be processed with injection molding or extrusion and is already getting good reviews from processors, Miller said, “particularly on the feeling — it’s not tacky. No PVC could do this.”

 At the three-day event in New York, Lubrizol also introduced medical device makers to Pathway, a new pharmaceutical-grade excipient aimed at TPU products for implantable controlled drug release devices. Implementing Good Manufacturing Practices (GMP), a pharma standard, at the company’s Wlimington, Mass., facility earlier this year opened the door for the first pharma-grade TPU in addition to Lubrizol’s medical-grade lines, said Joey Glassco, global market manager with Lubrizol LifeScience Polymers.

Drug loading into TPU devices can be achieved with blending and them melt-processing thermally stable drugs and then injection molding or extruding or by dissolving the polymer in compatible solvents — offering more processing versatility than silicone or ethyl vinyl acetate (EVA) competitors, Glassco said. The result is devices ideal for subcutaneous drug delivery systems, such as one that offers 30 to 90 day continuous opiate delivery for helping relive the pain of cancer patients in third-world countries or a variety of vaginal rings delivering birth control or other medications including tenofovir, an anti-microbial proven effective in combating HIV.


Comments

Lubrizol says new materials will bring more TPU to medical devices

By Gayle S. Putrich
Staff Reporter

Published: June 13, 2014 12:06 pm ET
Updated: June 13, 2014 12:14 pm ET

Post Your Comments


Back to story


More stories

Image

Citadel opens second compounding facility in China, near Shanghai

January 27, 2015 3:22 pm ET

Citadel Plastics Inc., the American manufacturer of thermoplastic and engineered composite compounds, has opened its second facility in China,...    More

Image

Sales, profit fall at DuPont

January 27, 2015 3:13 pm ET

Materials giant DuPont Co. will use almost all of the proceeds from an upcoming spinoff — one that includes its fluoropolymer and titanium...    More

Image

A. Schulman, Citadel continue buying blitz

January 27, 2015 11:32 am ET

A. Schulman Inc. and Citadel Plastics Inc. — two deal-happy materials firms — were at it again in the second half of 2014.    More

Image

It's becoming a seller's market for plastics firms

January 27, 2015 11:37 am ET

The pace of plastics mergers and acquisitions activity slowed a bit in the second half of 2014 — but market watchers have high expectations for ...    More

Image

Materials market sees more deals

January 27, 2015 11:26 am ET

Plastics materials deals showed modest growth in 2014, increasing 6 percent vs. their 2013 total.    More

Market Reports

Plastics in Automotive: Innovation & Emerging Trends

This special report newly released by PN and sponsored by The Conair Group examines current trends in the use of plastics in automotive, materials innovations and the changing landscape. It includes a review of legislative/regulatory activity impacting vehicle development and lightweighting, market opportunities & challenges for mold and toolmakers, innovative design strategies being implemented by major OEMs and suppliers, as well as a review of key indicators in Canada, Mexico, Brazil and China.

Learn more

Plastics Recycling Trends in North America

This report is a review and analysis of the North American Plastics Recycling Industry, including key trends and statistics based on 2013 performance. We examine market environment factors, regulatory issues, industry challenges, key drivers and emerging trends in post-consumer and post-industrial recycling.

Learn more

Injection Molding Market Analysis & Processor Rankings

Plastics News BUNDLED package contains our in-depth Market Analysis of the Injection Molding segment. You will gain keen insight on current trends and our economic outlook.

As a BONUS this includes PN's updated 2014 database of North American Injection Molders RANKED by sales volume. Sort, merge, mail & prospect by end market, materials processed, region, # of plants and more.

Learn more

Upcoming Plastics News Events

February 4, 2015 - February 6, 2015Plastics News Executive Forum 2015

June 2, 2015 - June 3, 2015Plastics Financial Summit - Chicago 2015

September 16, 2015 - September 18, 2015Plastics Caps & Closures - September 2015

More Events