EXETER, ENGLAND (Feb. 27, 11:30 a.m. ET) — A study that followed people over a 10-year period shows that healthy individual's with high urine concentrations of bisphenol A were more likely to later develop heart disease.
The researchers added, however, that they “can't be certain that BPA itself is responsible.” More research needed to determine whether the link is causal, they concluded.
The research team at the University of Exeter's Peninsula College of Medicine and Dentistry and the European Centre for the Environment and Human Health in association with the University of Cambridge had previously identified a link between BPA and an increased risk of cardiovascular disease by using two sets of U.S. data. These showed a correlation between exposure to BPA and heart problems, but they could not help researchers to predict how exposure to the chemical might affect future health.
The most recent study uses data from the European Prospective Investigation of Cancer (EPIC) in Norfolk, a long-term study led by the University of Cambridge, supported by the Medical Research Council UK and Cancer Research UK. It is the first time that data has been used to establish a link between exposure to BPA and future onset of cardiovascular disorders.
The study compared urine BPA measures from 758 initially healthy respondents who later developed cardiovascular disease, and 861 respondents who remained free from heart disease.
According to the findings, those who developed heart disease tended to have higher urinary BPA concentrations at the start of the 10-year period.
Professor David Melzer of the Peninsula Medical School, who led the team, said: “It is now important that government agencies organize drug style safety trials of BPA in humans, as much basic information about how BPA behaves in the human body is still unknown.”
The analysis, which was funded by the British Heart Foundation, has been published online in Circulation – a Journal of the American Heart Association.